Research Fellow

Description:

The University of Warwick is seeking a highly motivated Research Fellow for a Leverhulme Trust funded project, focusing on the respiration-fermentation flux switch in yeast. This position involves experimental work at the single-cell level, combining mathematical modelling and experimental techniques to study co-substrate dynamics, particularly NADH, in regulating metabolic fluxes.

The ideal candidate will have expertise in quantitative biology, cell biology, biochemistry, or biophysics, and should be familiar with techniques such as fluorescent microscopy, microfluidics, metabolomics, and transcriptomics. The role involves close collaboration with the research group of Dr. Orkun Soyer at Warwick and Prof. Wenying Shou at UCL, working with state-of-the-art facilities including a two-photon microscope and other -omics, microfluidics, and robotics technologies.

Candidates should have a strong background in experimental design and execution, particularly in cell culture and yeast-based experiments. The role will contribute to advancing the understanding of metabolic regulation, with implications in both microbial and mammalian cells.

Key Responsibilities:

• Conduct experimental research in quantitative biology, focusing on the regulation of the respiration-fermentation switch in yeast.
• Use advanced techniques such as fluorescent microscopy, microfluidics, and metabolomics.
• Collaborate with research teams at the University of Warwick and University College London.
• Contribute to publications in top-tier journals and present findings at international conferences.
• Participate in the mentoring of students and researchers within the lab.

About You:

• You should have a PhD in a relevant discipline (quantitative biology, cell biology, biochemistry, biophysics, or microbial physiology).
• Proficiency in key experimental techniques is required, including cell culture, microfluidics, and various omics technologies.
• Candidates nearing completion of their PhD or recently awarded a PhD are encouraged to apply.

About The Department:

The School of Life Sciences at the University of Warwick is renowned for its research in quantitative biology and cell metabolism. The research group of Dr. Orkun Soyer is at the forefront of studying metabolic interactions and the regulation of cell metabolism.